TWGFD

Welcome to bZIP !

The bZIP transcription factor family is highly conserved in plants, whose domain comprises 60-80 amino acids. It harbors a basic DNA binding region and a leucine zipper dimerization motif. The DNA binding region consists of an invariant N-?×?7-R/K-?×?9 motif with 18 amino acids. It regulates nuclear localization and DNA binding. The leucine zipper region comprises several repeats of leucine and/or other hydrophobic amino acids such as Ile, Val, Phe, and Met. bZIP proteins preferentially bind ACGT cores such as G-boxes (CACGTG), C-boxes (GACGTC), and A-boxes (TACGTA). bZIP proteins regulate transcription by interacting with the cis-elements in the promoter region and inducing or repressing multiple downstream genes and also play significant roles in plant responses to abiotic stress such as drought, salinity, cold and heat.