TWGFD

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Zinc-finger transcription factors (TF), one of the largest TF families in plants, play important roles in various cellular functions and multiple biological processes, such as morphogenesis, transcriptional activation, and environmental stress responses. The really interesting new gene (RING) finger belongs to the family of zinc finger domains first identified as a DNA-binding motif in the transcription factor TFIIIA from Xenopus laevis and comprises 40-60 amino acids that bind two atoms of zinc. In addition to DNA binding, it also binds RNA, proteins, or lipid substrates. Many proteins that harbor RING domain(s) are crucial for plant development and cellular processes, including gametogenesis, transcription regulation and signal transduction. Functions attributed to the RING domain itself include protein-protein interactions and ubiquitination.