TWGFD

Welcome to Caleosins !

Caleosins are calcium-binding proteins encoded by small gene families in plants, and some members of the gene family have been shown to play an important role in signaling and in the response to stress. Plants' responses to water deficit are known to activate signal transduction cascades that increase the level of secondary messengers, including calcium, thus some members of the caleosin gene family appear to play a critical role in water deficit signaling and to link calcium regulation to G protein signaling. The hairpin-like caleosins which are present in higher plants, fungi, and some of single-cell alga, have three characteristic motifs: The hydrophilic N-terminal domain contains an EF-hand calcium-binding domain; the hydrophobic domain in the centre of the protein contains a proline knot; phosphorylation sites are located in the hydrophilic C-terminal domain.