TWGFD

The tetraploid wheat gene family database

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Welcome to CDPK !

Calcium-dependent protein kinases (CDPKs) are important with regard to the abiotic stress resistance of plants. They are affected by the calcium (Ca2+) levels in plant cells. The calcium ion (Ca2+) plays central roles in the regulation of different physiological processes in plants as an important secondary messenger. Several major classes of Ca2+ binding proteins have been characterized in plants, including Ca2+-dependent protein kinases (CDPK), calmodulin (CaM), CAM-like proteins (CML), and calcineurin B-like proteins (CBL). Among these, CDPK constitutes a large calcium-sensing family only found in plants, protists, oomycetes, and green algae, and not in animals and fungi. CDPK structures include four domains: N-terminal, self-regulatory/autoinhibitory, serine/threonine kinase, and finally calmodulin-like regulatory domains (CaM-LD). CDPKs are involved in stress signaling, hormone response, and metabolic pathway regulation.