TWGFD

Welcome to CO-like !

The CONSTANS (CO) genes encode a small class of transcription factors, characterised by a CCT (CO, CO-like, TOC1 (TIMING OF CAB EXPRESSION1)) domain near the carboxy terminus. The CO-like gene family is subdivided into three groups according to the additional B-box domain near the amino terminus. The genes of Groups I, II, and III have two, one and one zinc-finger B-boxes, respectively; moreover, Group III genes contain a diverged B-box. The CCT domain is involved in nuclear localisation of CO proteins, and the B-box plays vital roles in protein-protein interactions. CONSTANS-like (CO-like, COL) genes play a vital role in the regulation of plant flowering through the photoperiod pathway, integrating the circadian clock, light signals and meristem genes identified as flowering time controls.