TWGFD

Welcome to Dof !

DNA-binding with one finger (Dof) proteins comprise a plant-specific transcription factor family, which is defined by the presence of the highly conserved Dof domain at the N-terminus. The Dof domain, which includes approximately 52 amino acids with a C2C2 zinc finger structure, mediates DNA binding as well as protein-protein interactions. By contrast, the C-terminal region of Dof proteins, which usually contains a transcriptional activation domain, is highly variable. Functional analysis performed in several species also revealed diverse roles of Dof proteins in various biological processes, for example, light-mediated regulation, vascular system development, flowering control, flower abscission, pollen development, endosperm development, seed development and germination, carbon and nitrogen metabolism, hormone, and stress responses.