TWGFD

Welcome to GAPDH !

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), catalyzing the conversion of glyceraldehyde-3-phosphate (G3P) to 1,3-biphosphoglycerate in the presence of NAD+ and inorganic phosphate, is a key enzyme in the glycolytic pathway. GAPDH was once considered as a simple “housekeeping gene” and has been used as a reference in gene expression and protein studies. GAPDHs play key roles in diverse cellular processes, including autophagy, mRNA regulation, gene expression regulation, immune response, redox sensing, and even photosynthesis.