TWGFD

Welcome to GSTs !

Glutathione transferases (GSTs) are multifunctional enzymes that are widely distributed in various organisms. GSTs contain an N-terminal domain and a C-terminal domain. The N-terminal domain includes a catalytic residue for glutathione (GSH) binding and catalysis, whereas the less conserved C-terminal domain, comprising five or six major helices, binds hydrophobic substrates and determines GST specificity and activity. GSTs play important roles in responses to biotic and abiotic stresses, such as pathogen attack, heavy metals, drought and salt, as well as salicylic acid signaling.