TWGFD

Welcome to MADS !

The MADS-box family genes encode transcription factors (TFs), which are widely distributed in eukaryotes and play fundamental roles in developmental control and signal transduction in eukaryotes. The MADS-box transcription factors were initially identified as floral organ identity-determination genes, and play important roles in plant development especially reproduction. The name MADS-box is derived from the initials of four transcription factors that were first discovered of this family: MINICHROMOSOME MAINTENANCE 1 (MCM1), AGAMOUS (AG), DEFICIENS (DEF), and SERUM RESPONSE FACTOR (SRF). Their N-terminal contains a highly conserved DNA-binding MADS-domain containing 56-60 amino acids.