TWGFD

The tetraploid wheat gene family database

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The family of aquaporins (AQPs), or major intrinsic proteins (MIPs), includes integral membrane proteins that function as transmembrane channels for water and other small molecules of physiological significance. Plant MIPs were originally categorized into four subfamilies on the basis of sequence homologies and subcellular localization: plasma membrane (PIP), tonoplast (TIP), nodulin-like (NIP) and small basic (SIP) intrinsic proteins. In addition, AQPs can also transport many small molecules, such as glycerol, urea, carbon dioxide (CO2), silicon, boron, ammonia (NH3) and hydrogen peroxide (H2O2).