TWGFD

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The plant metal tolerance proteins (MTPs) are divalent-cation/H+ antiporters and generally effluxers of metals out of the cytoplasm. MTPs usually act as homodimers and contain six transmembrane domains (TMDs) with cytosolic N- and C-terminals. MTPs mainly transport Mn, Zn and Fe metals but they also have affinities for other divalent cations such as Ni or Cd. MTPs are classified based on their metal specificities, as either of the Mn-, Zn- or Fe/Zn- CDF (cation diffusion facilitator family) type. MTPs play an important role in the transport of metals at the cellular, tissue and whole plant levels.