TWGFD

Welcome to NAC !

The NAC domain protein family is a larger plant-specific TF family. The family name is based on the three proteins: no apical meristem (NAM), ATAF1-2, and cup-shaped cotyledon (CUC), which all possess a similar DNA-binding domain. Typically, the structure of NAC proteins can be divided into conserved N-terminal DNA-binding domains and highly dispersed C-terminal transcriptional regulatory regions. NAC domains comprise five subdomains, A through E, located at the N-terminal, and usually contain approximately 150 amino acid residues, which are related to DNA binding, dimer formation and localization. NAC transcription factors have multiple functions in plants, such as the formation of plant shoot apical meristems, nutrient transfer, control of the cell cycle in plant senescence, the plant stress response, regulation of plant disease resistance and secondary growth, and hormone signaling.