TWGFD

Welcome to Whirly !

WHIRLY (Why) proteins are recognized as transcription factors (TF) in the nucleus. This small family of single-stranded DNA binding proteins is involved in control of defense gene expression. They also influence nuclear transcription and telomere maintenance, and that associate with nucleoids in chloroplasts and mitochondria. WHIRLY proteins contain a highly conserved WHIRLY domain, a KGKAAL residue contributing single strand DNA binding (SSB) function and YDW & Lys188 residues. AtWHY1 expression can be induced by salicylic acid (SA) treatment, which shows its role in SA-dependent resistance. Whirly constitutes one of the important TF families which plays essential roles in plant metabolism to cope with environmental stresses.