TWGFD
The tetraploid wheat gene family database
Welcome to Wox !
The WUSCHEL-related homebox (WOX) gene family is a unique transcription factor in plants and belongs to the homeobox (HB) superfamily. Its members all contain homeodomain (HD) with 60-66 amino acid residues. The specificity of the HD domain sequence makes the WOX gene family different from other HB families. The homeodomain binds DNA through a helix-turn-helix (HTH) structure. The HTH motif is characterized by two α-helices, which make intimate contacts with the DNA and are joined by a short turn. WOX genes have a wide range of functions, including embryonic development, embryonic polarization, maintenance of meristematic stem cells, development of lateral organs, seed formation and regeneration of isolated tissues and organs.